Description

2-(5-Phenyl-2H-Tetrazol-2-Yl)Ethanesulfonyl Fluoride is a specialized organosulfur and organofluorine compound that serves as a high-value synthetic intermediate. Its unique structure, combining a tetrazole ring with a sulfonyl fluoride moiety, makes it a critical building block for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, chemical biology, and the development of covalent inhibitors.

Application

• Medicinal Chemistry & Drug Discovery: A key precursor for synthesizing sulfonamide-based drug candidates and covalent enzyme inhibitors, leveraging the reactive sulfonyl fluoride group for selective protein modification.
• Chemical Biology & Proteomics: Used as a chemical probe or linker in activity-based protein profiling (ABPP) to study enzyme function and identify novel drug targets.
• Agrochemical Research: Serves as an intermediate in the synthesis of novel herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Material Science: Potential building block for advanced polymers and functional materials requiring specific chemical handles for further modification.
• Bioconjugation: Enables the site-specific labeling of biomolecules (proteins, peptides) for diagnostic and therapeutic applications.
• Academic & Contract Research: Employed in university and CRO laboratories for fundamental research in heterocyclic and organofluorine chemistry.

Basic Information

Product Name	2-(5-Phenyl-2H-Tetrazol-2-Yl)Ethanesulfonyl Fluoride
CAS No.	923723-76-6
Molecular Formula	C9H9FN4O2S
Molecular Weight	256.26 g/mol
Synonyms	2-(5-Phenyl-2H-tetrazol-2-yl)ethanesulfonyl fluoride; 2-(5-Phenyl-1H-tetrazol-2-yl)ethanesulfonyl fluoride; 2-(5-Phenyltetrazol-2-yl)ethanesulfonyl fluoride; 2-(5-Phenyl-2H-tetrazol-2-yl)ethane-1-sulfonyl fluoride; Ethanesulfonyl fluoride, 2-(5-phenyl-2H-tetrazol-2-yl)-; Tetrazole sulfonyl fluoride derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Typical: 97-99%)
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.