Description

Methyl 1-(Chlorosulfonyl)Piperidine-4-Carboxylate is a high-value, multi-functional piperidine derivative and a key synthetic intermediate in advanced organic chemistry. Its core value lies in its dual reactive sites—the chlorosulfonyl and ester groups—which enable efficient derivatization for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of potential drug candidates, including kinase inhibitors, receptor modulators, and other bioactive molecules containing the piperidine scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where the piperidine moiety can contribute to biological activity.
• Chemical Research & Development: Serves as a versatile precursor for creating custom libraries of sulfonamide and carboxylic acid derivatives for screening and lead optimization.
• Material Science: Can be utilized in the synthesis of specialty polymers, ligands for catalysis, or advanced materials requiring specific functional group integration.

Basic Information

Product Name	Methyl 1-(Chlorosulfonyl)Piperidine-4-Carboxylate
CAS No.	923681-70-3
Molecular Formula	C8H14ClNO4S
Molecular Weight	255.72 g/mol
Synonyms	1-(Chlorosulfonyl)-4-(methoxycarbonyl)piperidine; Methyl 4-(Chlorosulfonylcarboxylate)piperidine; Piperidine-4-carboxylic acid, 1-(chlorosulfonyl)-, methyl ester; 1-Chlorosulfonyl-piperidine-4-carboxylic acid methyl ester; Methyl piperidine-4-carboxylate-1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Our Methyl 1-(Chlorosulfonyl)Piperidine-4-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistent chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.