Description

3,5-Dimethylpiperidine-1-Sulfonyl Chloride is a specialized sulfonyl chloride derivative of a substituted piperidine, serving as a high-value building block in advanced organic synthesis. This compound is critical for introducing the sterically hindered 3,5-dimethylpiperidine-1-sulfonyl moiety, which can impart unique conformational and binding properties to target molecules. It is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, metabolic diseases, and oncology.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, where the sulfonamide group can contribute to biological activity and metabolic stability.
• Chemical Biology Probe Development: Employed to create sulfonamide-based probes and inhibitors for studying enzyme function and protein-protein interactions in biological systems.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers with specific functional groups.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke intermediates under cGMP or research-grade conditions.

Basic Information

Product Name	3,5-Dimethylpiperidine-1-Sulfonyl Chloride
CAS No.	923249-49-4
Molecular Formula	C7H14ClNO2S
Molecular Weight	211.71 g/mol
Synonyms	1-(Chlorosulfonyl)-3,5-dimethylpiperidine; 3,5-Dimethyl-1-piperidinesulfonyl chloride; 3,5-Dimethylpiperidine-1-sulfonyl chloride; 3,5-Dimethylpiperidine sulfonyl chloride; N-(Chlorosulfonyl)-3,5-dimethylpiperidine; Piperidine, 3,5-dimethyl-, 1-sulfonyl chloride
EINECS	Contact for details

Quality Control

Every batch of 3,5-Dimethylpiperidine-1-Sulfonyl Chloride is manufactured and tested under strict quality management protocols to ensure high purity and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (by HPLC or titration), identity confirmation (by IR and/or NMR), and impurity profiles. Our quality systems support development from research scale to pre-clinical cGMP standards, ensuring reliable supply for critical R&D and early-phase manufacturing projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.