Description

2-[[(4-Fluorophenyl)Sulfonyl](Methyl)Amino]Ethanesulfonyl Fluoride is a specialized organosulfur compound featuring a sulfonyl fluoride moiety, a key functional group in modern chemical synthesis. This compound matters as a versatile and reactive building block, enabling the precise construction of complex molecules through sulfur(VI) fluoride exchange (SuFEx) click chemistry and other advanced transformations. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel sulfonamide-based active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of novel sulfonamide drugs, including protease inhibitors and kinase inhibitors.
• SuFEx Click Chemistry Reagent: Utilized in sulfur(VI) fluoride exchange reactions for the rapid and reliable construction of chemical libraries and bioconjugates.
• Agrochemical Synthesis: Serves as a precursor in the development of new herbicides and fungicides with sulfonyl fluoride pharmacophores.
• Chemical Biology Probe Development: Used to create activity-based probes for profiling enzyme activity and studying biological pathways.
• Polymer & Material Science: Employed in the synthesis of functional polymers and advanced materials with tailored surface properties.
• Organic Synthesis Research: Acts as a key electrophile in academic and industrial research for exploring new C-S and C-N bond-forming reactions.

Basic Information

Product Name	2-[[(4-Fluorophenyl)Sulfonyl](Methyl)Amino]Ethanesulfonyl Fluoride
CAS No.	923138-37-8
Molecular Formula	C9H11F2NO4S2
Molecular Weight	299.31 g/mol
Synonyms	N-Methyl-N-(4-fluorophenylsulfonyl)taurine sulfonyl fluoride; 2-[(Methyl(4-fluorophenyl)sulfonyl)amino]ethanesulfonyl fluoride; 2-[(4-Fluorobenzenesulfonyl)(methyl)amino]ethanesulfonyl fluoride; Ethanesulfonyl fluoride, 2-[[(4-fluorophenyl)sulfonyl](methyl)amino]-; N-Methyl-N-(4-fluorophenylsulfonyl)-2-aminoethanesulfonyl fluoride; 923138-37-8; 4-Fluoro-N-methyl-N-(2-(fluorosulfonyl)ethyl)benzenesulfonamide
EINECS	Contact for details

Quality Control

Our 2-[[(4-Fluorophenyl)Sulfonyl](Methyl)Amino]Ethanesulfonyl Fluoride undergoes rigorous quality testing to ensure compliance with industry standards for high-purity research chemicals. Certificates of Analysis (COA) are available upon request, detailing purity, identity, and impurity profiles. We adhere to strict internal quality management protocols to ensure batch-to-batch consistency and reliability for your critical synthetic applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in a desiccator to prevent decomposition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.