Description

5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is a high-value fluorinated heterocyclic building block essential for modern pharmaceutical and agrochemical research. This compound serves as a critical intermediate in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor development. It is primarily utilized by research institutions and manufacturing organizations in the pharmaceutical, agrochemical, and advanced material science sectors seeking to incorporate its unique pyrrolopyridine scaffold into new molecular entities.

Application

• Pharmaceutical Intermediate: A key synthon for the development of kinase inhibitors, anticancer agents, and other small-molecule therapeutics.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators leveraging its heterocyclic core.
• Chemical Biology: Serves as a versatile scaffold for designing molecular probes and tool compounds in drug discovery programs.
• Material Science Precursor: Potential building block for advanced organic electronic materials and ligands in catalytic systems.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid
CAS No.	920978-94-5
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	5-Fluoro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Fluoro-2-carboxy-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 920978-94-5; 5-Fluoro-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid; 5-Fluoropyrrolo[2,3-b]pyridine-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development applications. All products undergo rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.