Description

1-(2,6-Difluoro-3-Pyridinyl)-Ethanone is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique difluoropyridine scaffold, which is instrumental in modulating the biological activity and physicochemical properties of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, where it is used to create novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atoms enhance metabolic stability and bioavailability.
• Material Science Research: Acts as a precursor for the synthesis of specialized ligands, catalysts, and fluorinated organic materials.
• Chemical Biology: Employed as a probe or labeling agent in medicinal chemistry for structure-activity relationship (SAR) studies.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions.

Basic Information

Product Name	1-(2,6-Difluoro-3-Pyridinyl)-Ethanone
CAS No.	920036-27-7
Molecular Formula	C7H5F2NO
Molecular Weight	157.12 g/mol
Synonyms	1-(2,6-Difluoropyridin-3-yl)ethanone; 2',6'-Difluoro-3-acetylpyridine; 3-Acetyl-2,6-difluoropyridine; Ethanone, 1-(2,6-difluoro-3-pyridinyl)-; 2,6-Difluoro-3-pyridyl methyl ketone; 2,6-Difluoro-3-acetylpyridine; 1-(2,6-Difluoro-3-pyridyl)ethan-1-one
EINECS	Contact for details

Quality Control

Our 1-(2,6-Difluoro-3-Pyridinyl)-Ethanone is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation supports regulatory filings for our global customer base.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.