Description

3-Difluoromethyl-Benzylamine is a high-value, fluorinated aromatic amine building block essential for advanced organic synthesis. Its unique structure, featuring a benzylamine core with a difluoromethyl substituent, makes it a critical intermediate for introducing specific physicochemical properties into target molecules. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries to develop novel active ingredients with enhanced metabolic stability and bioavailability.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can improve lipophilicity and biological activity.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials that require fluorinated aromatic components.
• Chemical Biology Probes: Useful for constructing molecular probes and tags for studying enzyme mechanisms and protein interactions in biochemical research.

Basic Information

Product Name	3-Difluoromethyl-Benzylamine
CAS No.	918810-95-4
Molecular Formula	C8H9F2N
Molecular Weight	157.16 g/mol
Synonyms	3-(Difluoromethyl)benzylamine; (3-(Difluoromethyl)phenyl)methanamine; α-(Difluoromethyl)-m-toluidine; m-(Difluoromethyl)benzylamine; 1-(Difluoromethyl)-3-(aminomethyl)benzene; Benzenemethanamine, 3-(difluoromethyl)-; 918810-95-4; 3-Difluoromethylbenzylamine
EINECS	Contact for details

Quality Control

Every batch of 3-Difluoromethyl-Benzylamine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A detailed Certificate of Analysis (COA) specifying purity, identity, and impurity profiles is supplied with each shipment to guarantee traceability and batch-to-batch consistency for your R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and acids. For long-term storage, consider storing under an inert atmosphere such as nitrogen to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.