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6-(Pyridin-3-Yloxy)Pyridine-3-Boronic Acid CAS NO 918138-38-2
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CAS No.:918138-38-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
6-(Pyridin-3-Yloxy)Pyridine-3-Boronic Acid is a high-purity boronic acid derivative, a crucial building block in modern synthetic chemistry. Its core value lies in enabling efficient cross-coupling reactions, such as the Suzuki-Miyaura reaction, which is fundamental for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials industries, where it is used to develop active pharmaceutical ingredients (APIs), novel crop protection agents, and organic electronic materials.
Application
- Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug candidates and active pharmaceutical ingredients (APIs) via palladium-catalyzed cross-coupling reactions.
- Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides by constructing biaryl and heterobiaryl structures.
- Material Science: Serves as a monomer or building block for creating conjugated polymers and organic semiconductors used in OLEDs, OFETs, and sensors.
- Chemical Synthesis: Enables the formation of carbon-carbon bonds in complex natural product synthesis and the preparation of functionalized ligands for catalysis.
- Library Synthesis: Employed in parallel and combinatorial chemistry for the rapid generation of diverse compound libraries for high-throughput screening.
Basic Information
| Product Name | 6-(Pyridin-3-Yloxy)Pyridine-3-Boronic Acid |
| CAS No. | 918138-38-2 |
| Molecular Formula | C10H9BN2O3 |
| Molecular Weight | 216.01 g/mol |
| Synonyms | 3-(5-Borono-2-pyridyloxy)pyridine; 6-(3-Pyridyloxy)-3-pyridineboronic acid; 6-(Pyridin-3-yloxy)pyridine-3-boronic acid pinacol ester (protected form); 5-Borono-2-(3-pyridyloxy)pyridine; 2-(Pyridin-3-yloxy)-5-pyridineboronic acid; [6-(3-Pyridinyloxy)-3-pyridinyl]boronic acid |
| EINECS | Contact for details |
Quality Control
Our 6-(Pyridin-3-Yloxy)Pyridine-3-Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high chemical purity and identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability and consistency for critical applications.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Water Content (KF) | ≤ 1.0% |
| Heavy Metals | ≤ 20 ppm |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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