Description

1-(5-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanol is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, combining a brominated pyridine ring with a trifluoroethanol moiety, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, including herbicides and fungicides, where the fluorine atoms enhance bioactivity and stability.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced materials with specific electronic or surface properties.
• Chemical Biology Probes: Useful for creating molecular probes and tags in biochemical research due to its reactive bromine and fluorine handles.

Basic Information

Product Name	1-(5-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanol
CAS No.	917397-92-3
Molecular Formula	C7H5BrF3NO
Molecular Weight	256.02 g/mol
Synonyms	2,2,2-Trifluoro-1-(5-bromo-2-pyridinyl)ethanol; 1-(5-Bromo-2-pyridyl)-2,2,2-trifluoroethanol; 5-Bromo-2-(2,2,2-trifluoro-1-hydroxyethyl)pyridine; α-(Trifluoromethyl)-5-bromo-2-pyridinemethanol; (5-Bromopyridin-2-yl)(trifluoromethyl)methanol
EINECS	Contact for details

Quality Control

Our production of 1-(5-Bromopyridin-2-Yl)-2,2,2-Trifluoroethanol adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced chromatographic and spectroscopic techniques (HPLC, GC, NMR) to verify identity, potency, and impurity profiles. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.