Description

Methyl 2-Methoxy-6-(Trifluoromethyl)Nicotinate is a high-value fluorinated nicotinate derivative, serving as a critical advanced intermediate in modern synthetic chemistry. Its core value lies in the trifluoromethyl group, which imparts unique physicochemical properties essential for developing compounds with enhanced metabolic stability and bioavailability. This product is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, as well as by fine chemical manufacturers producing specialized materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental persistence.
• Material Science Research: Serves as a precursor for developing specialty polymers and liquid crystals with specific optical or electronic properties.
• Fluorine Chemistry Studies: An important reagent for academic and industrial research exploring new methodologies in fluorination and heterocyclic chemistry.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value molecules for various industrial and research applications.

Basic Information

Product Name	Methyl 2-Methoxy-6-(Trifluoromethyl)Nicotinate
CAS No.	917396-36-2
Molecular Formula	C9H8F3NO3
Molecular Weight	235.16 g/mol
Synonyms	Methyl 2-methoxy-6-(trifluoromethyl)pyridine-3-carboxylate; 3-Pyridinecarboxylic acid, 2-methoxy-6-(trifluoromethyl)-, methyl ester; 2-Methoxy-6-(trifluoromethyl)nicotinic acid methyl ester; Methyl 2-methoxy-6-trifluoromethylnicotinate; 6-(Trifluoromethyl)-2-methoxynicotinic acid methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl 2-Methoxy-6-(Trifluoromethyl)Nicotinate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.