Description

3-Chloromethyl-2-Methyl-6-Trifluoromethyl-Pyridine is a high-value, multi-functional pyridine derivative that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both chloromethyl and trifluoromethyl groups, makes it an indispensable intermediate for creating complex molecules with tailored properties. This compound is primarily sought after by research and development teams and process chemists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized pyridine-based ligands used in transition metal catalysis for fine chemical production.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials with specific electronic or surface properties.
• Custom Synthesis and Contract Manufacturing: A vital reagent for custom synthesis organizations (CSOs) and CDMOs serving the life sciences sector.

Basic Information

Product Name	3-Chloromethyl-2-Methyl-6-Trifluoromethyl-Pyridine
CAS No.	917396-29-3
Molecular Formula	C8H7ClF3N
Molecular Weight	209.60 g/mol
Synonyms	2-Methyl-6-(trifluoromethyl)-3-pyridinemethanol, chloride; 3-(Chloromethyl)-2-methyl-6-(trifluoromethyl)pyridine; 2-Methyl-3-chloromethyl-6-trifluoromethylpyridine; 6-Trifluoromethyl-2-methyl-3-chloromethylpyridine; Pyridine, 3-(chloromethyl)-2-methyl-6-(trifluoromethyl)-; 3-Pyridinemethanol, 2-methyl-6-(trifluoromethyl)-, chloride
EINECS	Contact for details

Quality Control

Every batch of 3-Chloromethyl-2-Methyl-6-Trifluoromethyl-Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for sensitive synthetic applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles by HPLC, GC, and NMR is supplied with each shipment. Our quality commitment supports compliance in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.