Description

5-Fluoro-2-oxo-1,2-dihydropyridine-3-carbaldehyde is a high-purity fluorinated pyridone derivative, serving as a critical advanced pharmaceutical intermediate and versatile building block in organic synthesis. Its unique structure, featuring both a reactive aldehyde group and a fluorinated heterocyclic core, makes it indispensable for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in oncology and antiviral therapeutic areas.
• Agrochemical Synthesis: Used as a building block for creating advanced pesticides and herbicides with improved efficacy and selectivity.
• Organic Synthesis Reagent: Employed in cross-coupling reactions, condensation reactions, and as a precursor for more complex heterocyclic systems.
• Material Science Research: Investigated for the synthesis of specialized fluorinated organic materials and ligands for catalysis.
• Bioconjugation Chemistry: The aldehyde functionality allows for site-specific labeling and modification of biomolecules.

Basic Information

Product Name	5-Fluoro-2-oxo-1,2-dihydropyridine-3-carbaldehyde
CAS No.	917391-98-1
Molecular Formula	C6H4FNO2
Molecular Weight	141.10 g/mol
Synonyms	3-Formyl-5-fluoro-2-hydroxypyridine; 5-Fluoro-3-formyl-2(1H)-pyridinone; 5-Fluoro-2-hydroxy-3-pyridinecarboxaldehyde; 5-Fluoro-2-oxo-1,2-dihydro-3-pyridinecarbaldehyde; 5-Fluoro-2(1H)-pyridone-3-carboxaldehyde; 3-Pyridinecarboxaldehyde, 5-fluoro-1,2-dihydro-2-oxo-; 917391-98-1
EINECS	Contact for details

Quality Control

Our 5-Fluoro-2-oxo-1,2-dihydropyridine-3-carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.