Description

4-(Ethylthio)Phenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely utilized in advanced organic synthesis. Its core value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex sulfur-containing aromatic frameworks. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require a reliable building block for developing novel active ingredients and functional materials.

Application

• As a key Grignard reagent for nucleophilic addition reactions with carbonyl compounds (aldehydes, ketones, esters) to synthesize secondary and tertiary alcohols.
• Critical intermediate in the pharmaceutical research and development of drug candidates, particularly those containing aryl thioether motifs.
• Building block for the synthesis of liquid crystal materials and organic electronic compounds where the ethylthiophenyl group influences molecular alignment and electronic properties.
• Used in agrochemical synthesis for creating novel herbicides, fungicides, and insecticides with specific activity profiles.
• Precursor for the preparation of ligands used in catalysis and coordination chemistry.
• Employed in polymer chemistry to introduce functional aromatic side chains into polymer backbones.
• Facilitates cross-coupling reactions (e.g., Kumada coupling) as an organomagnesium coupling partner for carbon-carbon bond formation.

Basic Information

Product Name	4-(Ethylthio)Phenylmagnesium Bromide
CAS No.	917382-51-5
Molecular Formula	C8H9BrMgS
Molecular Weight	241.43 g/mol
Synonyms	p-(Ethylthio)phenylmagnesium bromide; (4-(Ethylthio)phenyl)magnesium bromide; 4-Ethylthiophenylmagnesium bromide; 1-Bromo-4-(ethylthio)benzene magnesium; Grignard reagent 4-(Ethylthio)phenyl; Magnesium, bromo[4-(ethylthio)phenyl]-; 4-(Ethylmercapto)phenylmagnesium bromide
EINECS	Contact for details

Quality Control

Every batch of 4-(Ethylthio)Phenylmagnesium Bromide is manufactured and tested under stringent quality management systems. We ensure product integrity through rigorous analytical controls, including titration to determine active reagent concentration and purity. Certificates of Analysis (COA) detailing batch-specific results are provided to guarantee consistency and support your research and development or production needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its nature as a highly volatile and easily oxidized Grignard reagent, it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C. Keep the container tightly sealed in a cool, dry, well-ventilated place, away from moisture and incompatible materials.

Specification

Item	Specification
Appearance	Solution (typically in THF or Diethyl Ether)
Concentration	0.5 M to 2.0 M in solvent (Customizable)
Assay (Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.