Description

4-Methoxyphenylmagnesium Bromide is a versatile Grignard reagent, an organomagnesium compound widely used in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, specifically introducing the 4-methoxyphenyl (anisyl) group into target molecules. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing active pharmaceutical ingredients (APIs), particularly those containing aryl ether motifs.
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and other crop protection agents that benefit from the anisyl functional group.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Fine Chemical and Dye Manufacturing: Employed in the production of complex organic molecules, including dyes, pigments, and photoinitiators.
• Material Science Research: Utilized in the synthesis of monomers and polymers for advanced materials with specific optical or electronic properties.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory organic synthesis in research settings.

Basic Information

Product Name	4-Methoxyphenylmagnesium Bromide
CAS No.	13139-86-1
Molecular Formula	C7H7BrMgO
Molecular Weight	211.34 g/mol
Synonyms	p-Anisylmagnesium Bromide; (4-Methoxyphenyl)magnesium Bromide; 4-Methoxybenzene Magnesium Bromide; 4-Methoxyphenyl Grignard Reagent; Magnesium, bromo(4-methoxyphenyl)-; Anisylmagnesium Bromide; 1-Methoxy-4-(bromomagnesio)benzene
EINECS	Contact for details

Quality Control

Our 4-Methoxyphenylmagnesium Bromide is produced and handled under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content, to ensure consistency and reliability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and solution concentration is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts vigorously with protic solvents. It must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from moisture, heat, and incompatible materials such as acids, oxidizers, and halogenated compounds.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Identification (IR/NMR)	Conforms to structure
Solvent (Typical)	Tetrahydrofuran (THF) or Diethyl Ether

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.