Description

Phenylmagnesium Iodide is a versatile organomagnesium halide, commonly known as a Grignard reagent, with the CAS registry number 16002-63-4. This compound is a critical intermediate in organic synthesis, prized for its ability to form carbon-carbon bonds and introduce phenyl groups into target molecules with high efficiency. It is an essential tool for research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to build complex molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing active pharmaceutical ingredients (APIs), particularly in the formation of biaryl structures and carbon-heteroatom bonds.
• Agrochemical Production: Used in the manufacture of herbicides, fungicides, and insecticides where the phenyl moiety is a core structural component.
• Fine Chemical and Specialty Chemical Manufacturing: Employed in the synthesis of dyes, pigments, liquid crystals, and other high-value aromatic compounds.
• Academic and Industrial R&D: Serves as a fundamental building block in method development and exploratory chemistry for creating novel organic molecules.
• Polymer Chemistry: Can be utilized to initiate polymerizations or to functionalize polymer chains with phenyl groups.
• Cross-Coupling Reactions: Acts as a phenyl nucleophile in various transition-metal catalyzed cross-coupling reactions, such as Kumada couplings.

Basic Information

Product Name	Phenylmagnesium Iodide
CAS No.	16002-63-4
Molecular Formula	C6H5MgI
Molecular Weight	204.31 g/mol
Synonyms	Magnesium, iodophenyl-; Phenylmagnesium Iodide Solution; Grignard Reagent C6H5MgI; Iodophenylmagnesium; Magnesium, (iodophenyl)-; Phenylmagnesium iodide, 1.0M solution in THF; (Iodophenyl)magnesium
EINECS	240-123-7

Quality Control

Our Phenylmagnesium Iodide is produced and handled under stringent quality management protocols. Each batch is analytically verified to ensure consistent reactivity and purity, typically supplied as a standardized solution in tetrahydrofuran (THF). A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as concentration (by titration), residual base content, and solvent purity. Our quality systems support compliance with cGMP and ISO standards for reliable integration into regulated synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, a strong base in organic solvent, and easily oxidized (store under inert atmosphere). It must be stored under a dry, inert atmosphere (argon or nitrogen) in a cool, well-ventilated area, away from heat, moisture, and incompatible materials such as acids, oxidizers, and protic solvents. For solutions, typical recommended storage temperature is 2-8°C to maintain stability and concentration. Always use appropriate techniques to exclude air and moisture during handling.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration (in THF)	0.5 - 2.0 M (Custom concentrations available)
Assay (Titration)	≥ 95% of stated concentration
Identification (IR/NMR)	Conforms to structure
Residual Base (as MgO)	Contact for details
Solvent (THF) Purity	≥ 99.5% (by GC)
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.