Description

Vinylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound in synthetic organic chemistry. Its primary value lies in its ability to efficiently introduce a vinyl group, serving as a critical building block for creating complex carbon skeletons. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, enabling the synthesis of key intermediates for active ingredients and specialty polymers. The compound is supplied as a solution in tetrahydrofuran, typically at concentrations of 1.0M or 1.6M, to ensure consistent reactivity and handling safety.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing carbon-carbon bonds in the synthesis of complex drug molecules and bioactive compounds.
• Agrochemical Production: Used in the manufacture of herbicides, fungicides, and insecticides that require vinyl-functionalized structures.
• Polymer & Material Science: Serves as a monomer or functionalization agent in the development of specialty polymers, coatings, and advanced materials.
• Fine Chemical Manufacturing: Employed in the production of flavors, fragrances, and other high-value specialty chemicals.
• Cross-Coupling Reactions: Acts as a vinyl nucleophile in Negishi, Kumada, and other transition metal-catalyzed coupling reactions.
• Academic & R&D Laboratories: A fundamental tool for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	Vinylmagnesium Bromide
CAS No.	1826-67-1
Molecular Formula	C2H3BrMg
Molecular Weight	131.25 g/mol
Synonyms	Ethenylmagnesium Bromide; Magnesium, bromoethenyl-; Bromo(vinyl)magnesium; Vinyl Grignard Reagent; Grignard Reagent Vinyl Bromide; (Vinyl)magnesium bromide; 1.0M Vinylmagnesium Bromide in THF; 1.6M Vinylmagnesium Bromide in THF
EINECS	217-374-9

Quality Control

Our Vinylmagnesium Bromide solutions are produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration (typically by titration), purity, and stability. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters. Our quality management system adheres to cGMP principles where applicable, supporting our commitment to supplying reliable reagents for critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C. The solution is highly volatile, easily oxidized, and reacts violently with water and protic solvents. Keep away from heat, sparks, open flames, and strong oxidizing agents. Use only in a well-ventilated fume hood with appropriate personal protective equipment.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF)	1.0 M or 1.6 M (Custom concentrations available)
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	< 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.