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Isopropenylmagnesium Bromide CAS NO 13291-18-4


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CAS No.:13291-18-4

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Isopropenylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound in advanced organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile for the efficient introduction of the isopropenyl group, enabling the construction of complex molecular frameworks. This reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to synthesize key intermediates for active ingredients and functional materials.

Application

  • Pharmaceutical Intermediate Synthesis: A key building block for creating complex drug molecules, particularly in the synthesis of steroids, prostaglandins, and other bioactive compounds.
  • Agrochemical Production: Used in the manufacture of advanced pesticides, herbicides, and plant growth regulators requiring specific olefinic side chains.
  • Polymer & Material Science: Serves as an initiator or co-monomer in the development of specialty polymers with tailored properties, such as impact modifiers or functionalized resins.
  • Fine Chemical Manufacturing: Employed in the production of flavors, fragrances, and other high-value specialty chemicals where precise carbon-carbon bond formation is critical.
  • Cross-Coupling Reactions: Acts as a coupling partner in transition metal-catalyzed reactions (e.g., Kumada coupling) to form new carbon-carbon bonds.
  • Academic & Industrial R&D: A fundamental tool in research laboratories for methodological development and exploring new synthetic pathways.

Basic Information

Product Name Isopropenylmagnesium Bromide
CAS No. 13291-18-4
Molecular Formula C3H5BrMg
Molecular Weight 145.28 g/mol
Synonyms 2-Propenylmagnesium Bromide; (1-Methylethenyl)magnesium Bromide; Magnesium, bromo(1-methylethenyl)-; Isopropenyl Grignard Reagent; Bromo(isopropenyl)magnesium; 2-Methyl-1-propenylmagnesium Bromide; 1-Propen-2-ylmagnesium Bromide
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Quality Control

Our Isopropenylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Each lot undergoes comprehensive analysis, including titration for active Grignard concentration and analysis of key impurities. A Certificate of Analysis (COA) detailing purity, concentration (typically supplied as a solution in THF or diethyl ether), and other relevant specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and pyrophoric nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) at temperatures recommended for the specific solvent formulation (typically between 2°C and 25°C). Store away from moisture, heat, and oxidizing agents in a cool, dry, well-ventilated area dedicated for flammable materials.

Specification

Item Specification
Appearance Clear, colorless to light yellow solution
Concentration 0.5 M to 2.0 M in specified solvent (e.g., THF, Diethyl ether)
Assay (Titration) ≥ 95% (as Grignard reagent)
Identification (IR/NMR) Conforms to structure
Solvent Specified (Tetrahydrofuran, Diethyl ether, etc.)
Water Content (Karl Fischer) < 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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