Description

Phenylmagnesium Bromide is a fundamental organometallic reagent, specifically a Grignard reagent, widely utilized in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile and strong base, enabling the formation of new carbon-carbon bonds. This compound is essential for research and industrial chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex aromatic frameworks.

Application

• Pharmaceutical Intermediates: Key reagent for synthesizing active pharmaceutical ingredients (APIs) and drug candidates through nucleophilic addition reactions.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and insecticides that require phenyl or substituted phenyl groups.
• Fine Chemical Manufacturing: Employed in the synthesis of complex organic molecules, including flavors, fragrances, and dyes.
• Polymer & Material Science: Serves as a building block for creating specialized polymers, liquid crystals, and organic electronic materials.
• Academic & R&D Laboratories: A staple reagent for methodological development and exploratory organic synthesis in research settings.
• Cross-Coupling Reactions: Acts as a phenyl source in various transition-metal catalyzed coupling reactions.

Basic Information

Product Name	Phenylmagnesium Bromide
CAS No.	100-58-3
Molecular Formula	C6H5MgBr
Molecular Weight	181.31 g/mol
Synonyms	Bromophenylmagnesium; Magnesium, bromophenyl-; Phenylmagnesium bromide solution; Grignard reagent C6H5MgBr; Bromo(phenyl)magnesium; Phenylmagnesium Bromide in THF; Phenylmagnesium Bromide in Diethyl Ether
EINECS	202-866-8

Quality Control

Our Phenylmagnesium Bromide is manufactured under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay, and impurity profiles. Our quality system is designed to meet the rigorous demands of GMP and ISO standards where applicable.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration (in THF)	1.0 M, 2.0 M, 3.0 M (or as specified)
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms to standard
Water Content (Karl Fischer)	≤ 0.05%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.