Description

8-Quinolinesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its ability to act as a sulfonylation reagent, facilitating the introduction of the 8-quinolinesulfonyl group to create novel compounds with targeted properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly in the development of active pharmaceutical ingredients (APIs), specialty dyes, and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in medicinal chemistry research targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of advanced pesticides, herbicides, and fungicides where the quinoline moiety imparts specific biological activity.
• Functional Material Precursor: Employed in the creation of specialty polymers, ligands for catalysis, and organic electronic materials.
• Dye and Pigment Manufacturing: Serves as an intermediate for synthesizing complex quinoline-based dyes and pigments.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and enzyme inhibition.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions to construct complex heterocyclic systems.

Basic Information

Product Name	8-Quinolinesulfonyl Chloride
CAS No.	917102-35-3
Molecular Formula	C9H6ClNO2S
Molecular Weight	227.67 g/mol
Synonyms	Quinoline-8-sulfonyl chloride; 8-Quinolinesulfonic acid chloride; 8-Quinoline sulfonyl chloride; 8-Sulfonylchloride quinoline; Quinoline-8-sulfonylchloride; 8-Quinolylsulfonyl chloride; 8-(Chlorosulfonyl)quinoline
EINECS	Contact for details

Quality Control

Our 8-Quinolinesulfonyl Chloride is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity verification and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, identity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.