Description

2,3,5,6-Tetrafluoropyridine-4-Propionic Acid is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring a propionic acid side chain on a perfluorinated pyridine ring, makes it an essential precursor for creating complex molecules with tailored properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of fluorinated drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides and pesticides, where fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs), improving dielectric anisotropy and thermal stability.
• Advanced Polymer Chemistry: Incorporated as a monomer or modifier to create specialty fluoropolymers with enhanced chemical resistance and surface properties.
• Organic Electronics: Employed in the development of electron-transport materials (ETMs) and other components for organic light-emitting diodes (OLEDs) and photovoltaic cells.
• Chemical Research & Development: A versatile reagent for introducing the tetrafluoropyridine moiety into complex molecular architectures in academic and industrial R&D settings.

Basic Information

Product Name	2,3,5,6-Tetrafluoropyridine-4-Propionic Acid
CAS No.	916792-08-0
Molecular Formula	C8H3F4NO2
Molecular Weight	221.11 g/mol
Synonyms	4-(2-Carboxyethyl)-2,3,5,6-tetrafluoropyridine; 3-(2,3,5,6-Tetrafluoro-4-pyridinyl)propanoic Acid; Tetrafluoropyridine-4-propionic Acid; 2,3,5,6-Tetrafluoro-4-pyridinepropanoic Acid; Perfluoropyridine-4-propionic Acid; TFPA (abbrev.); 916792-08-0; 4-Pyridinepropanoic acid, 2,3,5,6-tetrafluoro-
EINECS	Contact for details

Quality Control

Every batch of 2,3,5,6-Tetrafluoropyridine-4-Propionic Acid is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency essential for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which may affect product stability and performance.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.