Description

3-Fluoro-2-Methoxybenzyl Bromide is a versatile and high-purity organobromide building block essential for advanced organic synthesis. Its molecular structure, featuring both fluorine and methoxy substituents adjacent to a reactive benzyl bromide group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for applications such as drug discovery and the synthesis of functional materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing fluorinated benzyl motifs which can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, where the fluorine atom can improve biological activity and environmental persistence.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its ability to modify molecular architecture and properties.
• Chemical Biology Probes: Useful for synthesizing fluorinated probes and tags for studying biological systems and mechanisms of action.

Basic Information

Product Name	3-Fluoro-2-Methoxybenzyl Bromide
CAS No.	916420-50-3
Molecular Formula	C8H8BrFO
Molecular Weight	219.05 g/mol
Synonyms	1-(Bromomethyl)-3-fluoro-2-methoxybenzene; (3-Fluoro-2-methoxyphenyl)methyl Bromide; 2-Methoxy-3-fluorobenzyl Bromide; α-Bromo-3-fluoro-2-methoxytoluene; 3-Fluoro-o-anisyl Bromide; 3-Fluoro-2-methoxybenzylbromide; 3-Fluoro-2-methoxybenzyl bromide; 916420-50-3
EINECS	Contact for details

Quality Control

Our 3-Fluoro-2-Methoxybenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0% (Standard Grade)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.