Description

5-Fluoropyridine-2-Carboxamide is a high-value fluorinated pyridine derivative, serving as a critical building block in modern synthetic chemistry. Its unique structure, featuring both a fluorine atom and a carboxamide group on the pyridine ring, makes it an essential intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced bioavailability and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Employed in the design of molecular probes and tags for studying biological processes and protein interactions.
• Material Science: A building block for advanced polymers and functional materials requiring specific electronic or photophysical properties.

Basic Information

Product Name	5-Fluoropyridine-2-Carboxamide
CAS No.	916314-03-9
Molecular Formula	C6H5FN2O
Molecular Weight	140.11 g/mol
Synonyms	2-Carbamoyl-5-fluoropyridine; 5-Fluoro-2-pyridinecarboxamide; 5-Fluoropicolinamide; 5-Fluoropyridine-2-carboxylic acid amide; 2-Pyridinecarboxamide, 5-fluoro-; 916314-03-9
EINECS	Contact for details

Quality Control

Our 5-Fluoropyridine-2-Carboxamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/IR for structural confirmation, to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong acids, bases, and oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.