Description

Girentuximab CAS NO 916138-87-9 is a monoclonal antibody specifically designed for targeted therapeutic applications. This compound is of significant interest in the development of precision oncology treatments due to its selective binding properties. It is primarily utilized by pharmaceutical research organizations, biotechnology companies, and clinical development teams focused on innovative cancer therapies.

Application

• Targeted Cancer Therapy: Primary application in the research and development of treatments for specific cancer types, particularly renal cell carcinoma.
• Diagnostic Imaging Agent: Used in conjunction with imaging technologies for the detection and localization of tumors expressing the targeted antigen.
• Preclinical and Clinical Research: Serves as a critical reagent in pharmacokinetic, pharmacodynamic, and efficacy studies.
• Biomarker Development: Employed in assays to validate and quantify the presence of the target antigen in biological samples.
• Conjugate Platform: Acts as a targeting moiety for antibody-drug conjugates (ADCs) or radioimmunoconjugates.
• Companion Diagnostic Development: Integral to creating diagnostic tests that identify patients likely to respond to therapy.

Basic Information

Product Name	Girentuximab
CAS No.	916138-87-9
Molecular Formula	Contact for details
Molecular Weight	Approx. 150 kDa (Monoclonal Antibody)
Synonyms	cG250; Chimeric G250; Girentuximab; Monoclonal Antibody cG250; Anti-Carbonic Anhydrase IX Monoclonal Antibody; cG250 Monoclonal Antibody; Rencarex®
EINECS	Contact for details

Quality Control

Our Girentuximab is manufactured under strict quality systems. Each batch is subjected to a comprehensive suite of analytical tests to ensure identity, purity, potency, and safety, adhering to relevant guidelines for biopharmaceutical intermediates. Certificates of Analysis (COA) detailing specifications such as purity (by SEC-HPLC), endotoxin levels, sterility, and binding affinity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. This product is hygroscopic (moisture-sensitive) and strictly light-sensitive; handle under appropriate conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder or clear to slightly opalescent solution
Identification (SDS-PAGE / ELISA)	Complies
Purity (SEC-HPLC)	≥ 95% Monomer
Protein Content (UV Absorbance)	As per COA
Endotoxin	< 1.0 EU/mg
Sterility (Membrane Filtration)	Sterile
Binding Activity (SPR or ELISA)	As per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.