Description

1,2-Bis(Bromomethyl)-4,5-Difluorobenzene is a high-value, multi-functional aromatic building block characterized by its reactive bromomethyl and fluorine substituents. This compound matters for its versatility as a key intermediate in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of complex drug molecules, particularly those requiring difluorobenzene or benzyl bromide motifs for bioactivity or metabolic stability.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides where the fluorine atoms enhance lipophilicity and biological activity.
• Ligand and Catalyst Preparation: Serves as a starting material for synthesizing specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Polymer and Material Science: Employed as a monomer or cross-linking agent for producing high-performance polymers, liquid crystals, and specialty resins with unique thermal or chemical resistance.
• Organic Electronic Materials: A potential building block for the synthesis of novel organic semiconductors or charge-transport materials used in OLEDs and photovoltaic cells.
• Chemical Research & Development: A versatile scaffold for medicinal chemistry and discovery chemistry programs exploring new chemical entities.

Basic Information

Product Name	1,2-Bis(Bromomethyl)-4,5-Difluorobenzene
CAS No.	915944-27-3
Molecular Formula	C8H6Br2F2
Molecular Weight	307.94 g/mol
Synonyms	4,5-Difluoro-1,2-bis(bromomethyl)benzene; 1,2-Bis(bromomethyl)-4,5-difluorobenzol; 4,5-Difluoro-o-xylene-α,α'-dibromide; α,α'-Dibromo-4,5-difluoro-o-xylene; 1,2-Di(bromomethyl)-4,5-difluorobenzene; 4,5-Difluoro-1,2-bis(bromomethyl)benzol; 915944-27-3
EINECS	Contact for details

Quality Control

Our 1,2-Bis(Bromomethyl)-4,5-Difluorobenzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. We provide comprehensive Certificates of Analysis (COA) with all shipments, detailing purity, identity, and impurity profiles to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.