Description

Sfrp-1 Inhibitor CAS NO 915754-88-0 is a specialized small molecule compound designed to selectively inhibit the Sfrp-1 (Secreted Frizzled-Related Protein 1) signaling pathway. This targeted action makes it a critical research tool for investigating the Wnt/β-catenin pathway and its role in cellular processes. It is primarily utilized by researchers and scientists in the fields of oncology, developmental biology, and regenerative medicine. The compound is essential for high-throughput screening, target validation, and mechanistic studies in both academic and pharmaceutical R&D settings.

Application

• Biomedical Research: Fundamental tool for studying the role of Sfrp-1 and Wnt signaling in cell proliferation, differentiation, and apoptosis.
• Oncology Research: Used to investigate tumorigenesis, cancer cell stemness, and metastasis mechanisms where the Wnt pathway is dysregulated.
• Drug Discovery & Development: Serves as a reference compound or lead molecule in high-throughput screening campaigns for novel cancer therapeutics.
• Developmental Biology Studies: Applied in model organism research to understand embryonic development and tissue patterning.
• Regenerative Medicine: Used in studies exploring bone formation, tissue repair, and stem cell fate determination.
• Biochemical Assay Development: Acts as a key control in establishing and validating in vitro assays for Sfrp-1 activity.

Basic Information

Product Name	Sfrp-1 Inhibitor
CAS No.	915754-88-0
Molecular Formula	C19H15N3O3S
Molecular Weight	365.41 g/mol
Synonyms	WAY-316606; SFRP-1 Inhibitor, WAY-316606; (2E)-3-(6-Bromo-2-benzothiazolyl)-2-cyano-N-(3-methylphenyl)-2-propenamide; 2-Cyano-3-(6-bromo-2-benzothiazolyl)-N-(3-methylphenyl)-2-propenamide; SFRP1 Inhibitor; Secreted Frizzled-Related Protein 1 Inhibitor; Wnt Pathway Inhibitor
EINECS	Contact for details

Quality Control

Our Sfrp-1 Inhibitor is produced under strict quality management protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, identity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under inert atmosphere for long-term stability. For short-term use, the material may be stored at 2-8°C. The compound is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation.

Specification

Item	Specification
Appearance	Off-white to yellow solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (MS)	Consistent with molecular ion [M+H]+
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.