Description

5-Fluoro-6-Methyl-2-Pyridinecarbonitrile is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique molecular structure, which enables the introduction of both fluorine and nitrile functional groups into target molecules, facilitating the development of novel compounds with enhanced properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of active ingredients and complex heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, especially in kinase inhibitor and central nervous system (CNS) active molecule libraries.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atom can improve metabolic stability and bioavailability.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis projects and scale-up production under cGMP conditions for clinical trial materials.

Basic Information

Product Name	5-Fluoro-6-Methyl-2-Pyridinecarbonitrile
CAS No.	915720-64-8
Molecular Formula	C7H5FN2
Molecular Weight	136.13 g/mol
Synonyms	2-Cyano-5-fluoro-6-methylpyridine; 5-Fluoro-6-methylpicolinonitrile; 6-Methyl-5-fluoropyridine-2-carbonitrile; 5-Fluoro-6-methyl-2-cyanopyridine; 2-Pyridinecarbonitrile, 5-fluoro-6-methyl-; 915720-64-8; 5-Fluoro-6-methylpyridine-2-carbonitrile
EINECS	Contact for details

Quality Control

Our 5-Fluoro-6-Methyl-2-Pyridinecarbonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC, GC, NMR, and mass spectrometry, to verify identity and purity. Certificates of Analysis (COA) are available for every batch, and we support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.