Description

3-Pyrimidin-2-Ylbenzenesulphonyl Chloride is a high-purity sulfonyl chloride derivative, a crucial chemical intermediate in advanced organic synthesis. Its core value lies in its reactive sulfonyl chloride group, which enables efficient sulfonylation reactions for constructing complex molecular architectures. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel active ingredients and fine chemicals. The CAS number for this compound is 915707-50-5.

Application

This versatile sulfonyl chloride intermediate is primarily employed in the following areas:

• Pharmaceutical Intermediates: Key building block for the synthesis of sulfonamide-based drug candidates, including kinase inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides that require a sulfonyl moiety for bioactivity.
• Material Science Research: Serves as a precursor for creating functionalized polymers and advanced materials with specific surface properties.
• Chemical Biology & Proteomics: Acts as a reactive handle for labeling or modifying biomolecules in probe development and activity-based protein profiling.
• Custom Synthesis & Contract Manufacturing: A critical raw material for custom synthesis houses producing specialized compounds for client R&D programs.

Basic Information

Item	Details
Product Name	3-Pyrimidin-2-Ylbenzenesulphonyl Chloride
CAS No.	915707-50-5
Molecular Formula	C10H7ClN2O2S
Molecular Weight	254.69 g/mol
Synonyms	3-(Pyrimidin-2-yl)benzenesulfonyl chloride; 2-(3-Chlorosulfonylphenyl)pyrimidine; m-(2-Pyrimidyl)benzenesulfonyl chloride; 915707-50-5; 3-Pyrimidin-2-yl-benzenesulfonyl chloride; 3-(2-Pyrimidinyl)benzenesulfonyl chloride
EINECS	Contact for details

Quality Control

Our production of 3-Pyrimidin-2-Ylbenzenesulphonyl Chloride adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We operate under a cGMP-compliant quality management system to meet the exacting standards of pharmaceutical and advanced chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in its original packaging to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.