Description

3-Bromobenzene-1-Sulfonyl Chloride is a high-purity aromatic sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its primary value lies in its dual reactive sites—the sulfonyl chloride and the bromo substituent—which enable sequential and selective functionalization for constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require reliable, high-quality intermediates for drug discovery and material science applications.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of sulfonamide-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and pesticides that incorporate sulfonyl functional groups.
• Material Science: Building block for creating functional polymers, dyes, and liquid crystals with specific electronic or optical properties.
• Cross-Coupling Reactions: The bromoaryl group makes it a suitable substrate for palladium-catalyzed reactions like Suzuki, Heck, or Sonogashira couplings.
• Chemical Biology Probes: Utilized in the design of activity-based probes and affinity labels for studying enzyme function and protein interactions.
• Sulfonylation Agent: Acts as an electrophilic sulfonylation reagent to introduce the sulfonyl moiety into various nucleophiles like amines and alcohols.

Basic Information

Product Name	3-Bromobenzene-1-Sulfonyl Chloride
CAS No.	915403-76-8
Molecular Formula	C6H4BrClO2S
Molecular Weight	255.52 g/mol
Synonyms	3-Bromobenzenesulfonyl chloride; m-Bromobenzenesulfonyl chloride; 1-Bromo-3-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 3-bromo-; 3-Bromophenylsulfonyl chloride
EINECS	Contact for details

Quality Control

Our 3-Bromobenzene-1-Sulfonyl Chloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to prevent decomposition. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, amines, and alcohols.

Specification

Item	Specification
Appearance	White to off-white crystalline solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.