Description

2,3,5-Trifluorobenzenesulfonyl Chloride, Jrd, 97% is a high-purity, multi-fluorinated aromatic sulfonyl chloride building block. This compound is a critical reagent in modern synthetic chemistry, valued for its ability to introduce the versatile sulfonyl group into target molecules while offering the unique electronic and steric properties imparted by the trifluoro substitution pattern. It is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, sulfonamides, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of sulfonamide-based drug candidates, including protease inhibitors and receptor antagonists.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the sulfonyl moiety enhances biological activity.
• Material Science Research: Serves as a precursor for creating functionalized polymers, liquid crystals, and other advanced materials with tailored properties.
• Chemical Derivatization: Employed in analytical chemistry and proteomics for labeling and modifying biomolecules.
• Cross-Coupling Reactions: Acts as an electrophile in palladium-catalyzed cross-coupling reactions to form carbon-sulfur bonds.
• Custom Synthesis & Contract Manufacturing: An essential reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Item	Details
Product Name	2,3,5-Trifluorobenzenesulfonyl Chloride, Jrd, 97%
CAS No.	914636-99-0
Molecular Formula	C6H2ClF3O2S
Molecular Weight	230.59 g/mol
Synonyms	2,3,5-Trifluorobenzenesulfonyl chloride; 2,3,5-Trifluorophenylsulfonyl chloride; 1,2,4-Trifluoro-5-(chlorosulfonyl)benzene; Benzenesulfonyl chloride, 2,3,5-trifluoro-; 914636-99-0; Jrd 2,3,5-Trifluorobenzenesulfonyl Chloride
EINECS	Contact for details

Quality Control

Our 2,3,5-Trifluorobenzenesulfonyl Chloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to confirm identity and assay. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and reacts with strong acids/organic solvents; ensure the container is kept tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent degradation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.