Description

2-Bromo-5-Isopropoxybenzotrifluoride is a high-value fluorinated aromatic building block, essential for advanced organic synthesis. Its unique structure, combining bromo, isopropoxy, and trifluoromethyl substituents, makes it a critical intermediate for creating complex molecules with tailored properties. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the trifluoromethyl group enhances bioactivity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated components in electronic display materials, improving dielectric anisotropy and thermal stability.
• Functional Material Research: Employed in academic and industrial R&D to create novel polymers, ligands for catalysis, and specialty chemicals with unique surface properties.
• Cross-Coupling Reactions: The bromine atom acts as an excellent handle for palladium-catalyzed reactions like Suzuki, Negishi, and Buchwald-Hartwig aminations, enabling rapid molecular diversification.

Basic Information

Product Name	2-Bromo-5-Isopropoxybenzotrifluoride
CAS No.	914635-70-4
Molecular Formula	C10H10BrF3O
Molecular Weight	283.09 g/mol
Synonyms	1-Bromo-4-isopropoxy-2-(trifluoromethyl)benzene; 2-Bromo-5-isopropoxy-α,α,α-trifluorotoluene; Benzene, 1-bromo-4-(1-methylethoxy)-2-(trifluoromethyl)-; 5-Isopropoxy-2-bromobenzotrifluoride; 2-Bromo-5-(1-methylethoxy)benzotrifluoride; 2-Bromo-5-isopropoxy-α,α,α-trifluoromethylbenzene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Isopropoxybenzotrifluoride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and batch-to-batch consistency suitable for sensitive synthetic applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.