Description

2-Bromo-3-Methoxybenzotrifluoride is a versatile fluorinated aromatic building block characterized by its bromine and methoxy substituents. This compound is highly valued in advanced organic synthesis for its role in facilitating cross-coupling reactions and serving as a key intermediate in the development of complex molecules. It is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and materials science sectors for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides where the benzotrifluoride scaffold imparts favorable biological activity and metabolic stability.
• Material Science Research: Serves as a building block for liquid crystals, organic semiconductors, and advanced polymers, leveraging its electronic properties and structural rigidity.
• Cross-Coupling Reactions: The bromine atom makes it an excellent substrate for Suzuki, Stille, and other palladium-catalyzed coupling reactions to form biaryl structures.
• Chemical Research & Development: Employed in academic and industrial R&D labs for exploring new synthetic methodologies and creating compound libraries for screening.

Basic Information

Product Name	2-Bromo-3-Methoxybenzotrifluoride
CAS No.	914635-64-6
Molecular Formula	C9H6BrF3O
Molecular Weight	255.04 g/mol
Synonyms	1-Bromo-2-methoxy-3-(trifluoromethyl)benzene; 3-Methoxy-2-bromobenzotrifluoride; 2-Bromo-3-methoxy-α,α,α-trifluorotoluene; 2-Bromo-3-methoxy-(trifluoromethyl)benzene; Benzene, 1-bromo-2-methoxy-3-(trifluoromethyl)-; (2-Bromo-3-methoxyphenyl)trifluoromethane
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Methoxybenzotrifluoride is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, and we support custom purity requirements for specific R&D or production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and bases. Recommended storage temperature is between 15°C and 25°C. The compound is light-sensitive and should be stored away from light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.