Description

Atosiban Acetate is a synthetic peptide antagonist of the oxytocin and vasopressin V1a receptors, widely used as a tocolytic agent. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the safety and efficacy of pharmaceutical formulations designed to manage preterm labor. It is primarily utilized by pharmaceutical manufacturers and research institutions in the development and production of therapeutic drugs. The compound is supplied under stringent quality control to meet the exacting standards of the global pharmaceutical industry.

Application

• Pharmaceutical API: Primary active ingredient in injectable formulations for the inhibition of premature labor (tocolysis).
• Clinical Research: Used in preclinical and clinical studies investigating uterine contractility and the mechanisms of preterm birth.
• Drug Development: Serves as a reference standard and key intermediate in the development of new tocolytic agents and related peptides.
• Biochemical Research: A vital tool for studying oxytocin and vasopressin receptor pathways in various physiological and pathological processes.

Basic Information

Product Name	Atosiban Acetate
CAS No.	914453-95-5
Molecular Formula	C45H70N12O14S2 • xC2H4O2
Molecular Weight	994.2 g/mol (as free base)
Synonyms	1-(3-Mercaptopropanoic acid)-2-(3-(p-ethoxyphenyl)-D-proline)-6-(N-ethyl-L-prolinamide)-9-L-proline Vasotocin Acetate; d(CH2)5[Tyr(Me)^2,Thr^4,Orn^8,Tyr-NH2^9]OVT Acetate; Tractocile (Brand Name); Antocin; RWJ 22164; Oxytocin Receptor Antagonist; Vasotocin Analog
EINECS	Contact for details

Quality Control

Our Atosiban Acetate is manufactured under cGMP conditions and undergoes rigorous analytical testing to ensure it meets the highest standards for pharmaceutical use. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We ensure compliance with relevant pharmacopeial guidelines (e.g., USP, EP) for peptide APIs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
Acetic Acid Content	5.0% - 12.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 10 EU/mg
Microbial Enumeration	Meets Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.