Description

Octreotide Acetate is a synthetic cyclic octapeptide analog of the natural hormone somatostatin. This compound is a critical active pharmaceutical ingredient (API) valued for its potent inhibitory effects on the secretion of growth hormone, glucagon, and insulin. It is essential for the formulation of therapeutic drugs used in endocrinology and oncology. Global pharmaceutical manufacturers and research institutions require this high-purity peptide for developing treatments for conditions like acromegaly, neuroendocrine tumors, and severe diarrhea.

Application

• Pharmaceutical API: Primary active ingredient in injectable formulations for treating acromegaly and gigantism.
• Oncological Therapeutics: Used in medications for symptom control of carcinoid syndrome and VIPomas.
• Research & Development: Critical reference standard and tool compound in endocrine and cancer research.
• Drug Delivery Systems: Incorporated into long-acting release (LAR) depot formulations and implants.
• Veterinary Medicine: Applied in the treatment of endocrine disorders in animals.
• Diagnostic Aid: Utilized in specialized diagnostic tests for hormone-secreting tumors.

Basic Information

Product Name	Octreotide Acetate
CAS No.	83150-76-9
Molecular Formula	C49H66N10O10S2 • xC2H4O2
Molecular Weight	1019.24 g/mol (free base)
Synonyms	Octreotide Acetate; SMS 201-995 Acetate; Sandostatin Acetate; D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide cyclic (2→7)-disulfide acetate; Cyclo(L-cysteinyl-D-phenylalanyl-L-cysteinyl-L-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threonyl(2→7)-disulfide) acetate; (R)-2,6-Diamino-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)hexanamide acetate salt
EINECS	Contact for details

Quality Control

Our Octreotide Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and potency. Certificates of Analysis (COA) are provided, detailing results from tests such as HPLC, amino acid analysis, and related substances. We support compliance with ICH Q7 guidelines, USP/EP monographs, and relevant GMP standards for API production.

Storage

Preserve in a tightly closed container, protected from light. Store at a controlled room temperature of 15-25°C or as specified on the label. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	98.0% - 102.0% (on anhydrous, acetic acid-free basis)
Water Content (KF)	≤ 8.0 %
Acetic Acid Content	4.0% - 12.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Bacterial Endotoxins	< 50 EU/mg
Microbial Enumeration	Complies with Ph. Eur. 2.6.12/2.6.13

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.