Description

Protirelin Acetate is a synthetic peptide analog of thyrotropin-releasing hormone (TRH), a key hypothalamic hormone. This high-purity compound is essential for research and development in endocrinology and neuropharmacology. It serves as a critical reference standard and active ingredient for scientists and manufacturers in the pharmaceutical and biotechnology sectors, particularly for diagnostic applications and advanced therapeutic studies.

Application

• Pharmaceutical Reference Standard: Used for the calibration and validation of analytical methods in quality control laboratories.
• Diagnostic Agent Development: A key component in the research and formulation of diagnostic kits for assessing thyroid and pituitary function.
• Neuroendocrine Research: Fundamental for in vitro and in vivo studies investigating the regulation of thyroid-stimulating hormone (TSH) and prolactin secretion.
• Preclinical Studies: Employed in animal models to study the central nervous system effects of TRH, including potential applications in neurology and psychiatry.
• Biochemical Reagent: Used in cell culture and molecular biology experiments to study receptor binding and signal transduction pathways.
• API Intermediate: Serves as a high-purity building block in the synthesis of more complex peptide-based active pharmaceutical ingredients (APIs).

Basic Information

Product Name	Protirelin Acetate
CAS No.	120876-23-5
Molecular Formula	C16H22N6O4 • xC2H4O2
Molecular Weight	362.39 g/mol (free base)
Synonyms	Thyrotropin-Releasing Hormone Acetate; TRH Acetate; Lopremone; Pyroglutamyl-histidyl-prolinamide Acetate; (pyro)Glu-His-Pro-NH2 Acetate; Tirelin Acetate; Protirelinum; Thyroliberin Acetate
EINECS	Contact for details

Quality Control

Our Protirelin Acetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, peptide content determination, and identity confirmation by mass spectrometry. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with research and development grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to maintain stability and purity. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Peptide Content	≥ 80.0%
Acetic Acid Content	5.0% - 12.0%
Water Content (KF)	≤ 5.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.