Description

Oxytocin Free Acid is the non-cyclic, linear precursor form of the neuropeptide hormone oxytocin, characterized by its free C-terminal carboxylic acid group. This molecular form is of significant value in biochemical research and pharmaceutical development, serving as a critical intermediate for the synthesis and study of oxytocin analogs and derivatives. It is primarily utilized by research institutions, biotechnology companies, and pharmaceutical manufacturers engaged in peptide chemistry, neuroendocrinology, and drug discovery programs.

Application

• Peptide Synthesis Intermediate: Serves as a key building block for the solid-phase or solution-phase synthesis of oxytocin and its structural analogs.
• Biochemical Research: Used in studies investigating the structure-activity relationships (SAR) of oxytocin, its receptor binding mechanisms, and metabolic pathways.
• Reference Standard: Employed as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method development.
• Pharmaceutical Development: Acts as a starting material or intermediate in the R&D of novel therapeutic agents targeting the oxytocin receptor for conditions like social disorders, postpartum hemorrhage, and autism spectrum disorders.
• Enzymatic Studies: Utilized as a substrate for enzymes involved in peptide processing and modification.

Basic Information

Product Name	Oxytocin Free Acid
CAS No.	24346-32-5
Molecular Formula	C₄₃H₆₆N₁₂O₁₂S₂
Molecular Weight	1007.2 g/mol
Synonyms	H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-OH (Disulfide bond: 1-6); Oxytocin (free acid); OXT (free acid); Pitocin (free acid); 1-{(4R,7S,10S,13S,16S,19R)-19-Amino-13-(2-amino-2-oxoethyl)-7-(2-amino-3-sulfanylpropyl)-10-(3-amino-3-oxopropyl)-16-[(4-hydroxyphenyl)methyl]-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaazacycloicosan-4-yl}-2-(methylamino)-2-oxoethane; L-Cysteinyl-L-tyrosyl-L-isoleucyl-L-glutaminyl-L-asparaginyl-L-cysteinyl-L-prolyl-L-leucylglycine (1->6)-disulfide
EINECS	Contact for details

Quality Control

Our Oxytocin Free Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for research and development use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Single Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.