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Parathyroid Hormone CAS NO 12584-96-2
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CAS No.:12584-96-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Parathyroid Hormone (PTH) is a critical peptide hormone essential for regulating calcium and phosphate homeostasis in the body. Its primary commercial and research value lies in its role as a key therapeutic target and diagnostic marker for bone and mineral disorders, particularly hypoparathyroidism and osteoporosis. This high-purity product is essential for pharmaceutical R&D, clinical diagnostics, and advanced biochemical studies, serving the needs of biotechnology firms, academic research institutions, and diagnostic manufacturers globally.
Application
- Pharmaceutical Research & Development: Critical for developing and testing novel therapeutics for bone diseases like osteoporosis and hypoparathyroidism.
- Clinical Diagnostics: Used as a reference standard in immunoassays (e.g., ELISA) to measure PTH levels in patient serum, aiding in the diagnosis of parathyroid gland disorders.
- Biochemical Studies: Employed in fundamental research to investigate calcium metabolism, bone biology, and hormone receptor interactions.
- Cell Culture & In Vitro Testing: Utilized as a bioactive agent to stimulate cellular responses in osteoblast and kidney cell line studies.
- Peptide Synthesis & Standardization: Serves as a high-purity benchmark or starting material for related peptide analog synthesis.
Basic Information
| Product Name | Parathyroid Hormone |
| CAS No. | 12584-96-2 |
| Molecular Formula | C181H291N55O51S2 |
| Molecular Weight | ~ 4117.8 g/mol |
| Synonyms | Parathormone; PTH (1-84); Parathyroid Hormone (1-84), Human; Human Parathyroid Hormone; PTH Human; Endocrine Hormone PTH; Parathyrin; Parathyrin (1-84); CAS 12584-96-2 |
| EINECS | Contact for details |
Quality Control
Our Parathyroid Hormone is manufactured under stringent conditions to ensure the highest standards of purity and biological activity. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and bioactivity assays. Certificates of Analysis (COA) detailing all specifications are provided to guarantee traceability and compliance with your research or production requirements.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep desiccated.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC/MS) | Conforms to standard |
| Purity (HPLC) | ≥ 95.0% |
| Peptide Content | ≥ 80.0% |
| Water Content (KF) | ≤ 5.0% |
| Biological Activity | Assessed by in vitro assay |
| Endotoxin Level | < 1.0 EU/μg |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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