Description

Argipressin Acetate is a synthetic peptide analog of the endogenous hormone vasopressin, modified for enhanced stability and pharmacological research. This compound is critical for studying vasoconstriction, antidiuretic mechanisms, and central nervous system functions in preclinical models. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and manufacturers of high-purity reference standards for analytical and investigative purposes.

Application

• Pharmacological Research: Used as a reference standard and active agent in studies of vasopressin receptor (V1a, V2) activity, cardiovascular function, and renal water reabsorption.
• Biochemical Assay Development: Serves as a critical component in the development and validation of bioassays, immunoassays, and receptor binding studies.
• Neuroscience Studies: Employed in research exploring the role of vasopressin in social behavior, memory, stress response, and thermoregulation within the central nervous system.
• Pharmaceutical Reference Standard: Provides a certified, high-purity material for quality control, method development, and regulatory submissions in peptide-based drug manufacturing.
• Preclinical Model Studies: Applied in animal models to investigate conditions related to diabetes insipidus, septic shock, hypertension, and bleeding disorders.

Basic Information

Product Name	Argipressin Acetate
CAS No.	129979-57-3
Molecular Formula	C46H65N15O12S2 • xC2H4O2
Molecular Weight	1084.2 g/mol (base peptide)
Synonyms	[8-Arginine]Vasopressin Acetate; Argipressin; AVP; Vasopressin, 8-Arg-; Antidiuretic Hormone (ADH) Acetate; 8-L-Arginine Vasopressin; Pitressin (synthetic analog); Pressyn AR
EINECS	Contact for details

Quality Control

Our Argipressin Acetate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing including HPLC for purity, MS for identity confirmation, and tests for related substances, residual solvents, and acetic acid content. We provide full traceability and Certificates of Analysis (COA) are available for every lot, ensuring compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, keep under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%; Total impurities ≤ 3.0%
Water Content (KF)	≤ 5.0%
Acetic Acid Content	5.0% - 12.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.