Description

Argipressin, Ser-Ala- CAS NO 115699-80-4 is a synthetic peptide analog of vasopressin, specifically modified at the serine and alanine positions. This modification is critical for enhancing its stability and receptor selectivity, making it a valuable research and pharmaceutical intermediate. It is primarily utilized in advanced biochemical research, drug discovery programs, and the development of therapeutic agents targeting vasopressin-related pathways. Industries involved in peptide synthesis, contract research, and pharmaceutical development are the key procurers of this high-purity compound.

Application

• Biochemical Research: Used as a reference standard and tool compound for studying vasopressin receptor (V1a, V1b, V2) pharmacology and signaling mechanisms.
• Pharmaceutical Development: Serves as a key intermediate in the synthesis of novel peptide-based therapeutics for conditions like diabetes insipidus, septic shock, and cardiovascular disorders.
• In Vitro Diagnostics: Employed in the development and calibration of immunoassays and diagnostic kits designed to measure vasopressin levels or related biomarkers.
• Neuroscience Studies: Applied in research investigating the role of vasopressin in social behavior, memory, stress response, and central nervous system function.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for GMP or non-GMP scale-up synthesis of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for fundamental studies in endocrinology, physiology, and peptide chemistry.

Basic Information

Product Name	Argipressin, Ser-Ala- CAS NO 115699-80-4
CAS No.	115699-80-4
Molecular Formula	C46H65N15O12S2
Molecular Weight	1084.2 g/mol
Synonyms	[Ser4, Ala9]-Vasopressin; [1-(L-Mercaptopropionic acid), 4-L-Serine, 9-L-Alanine] Vasopressin; Desmopressin analog; AVP (4-Ser, 9-Ala); Vasopressin Ser-Ala analog; Cyclo(1-6)-L-Cys-Tyr-Phe-Ser-Asn-Cys-Pro-Ala-Gly-NH2; H-Cys-Tyr-Phe-Ser-Asn-Cys-Pro-Ala-Gly-NH2 (cyclic 1-6 disulfide)
EINECS	Contact for details

Quality Control

Every batch of Argipressin, Ser-Ala- is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC for purity, MS for identity confirmation, and tests for related substances and residual solvents, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) detailing batch-specific results are available upon request. We can support development toward cGMP standards as required.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Total Impurities (HPLC)	≤ 5.0%
Water Content (KF)	≤ 8.0%
Peptide Content (Amino Acid Analysis)	≥ 80.0%
Solvent Residues (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.