Description

Argipressine is a synthetic nonapeptide analog of the endogenous hormone vasopressin, widely recognized for its potent vasoconstrictive and antidiuretic properties. This high-purity compound is essential for advanced pharmaceutical research and development, offering critical activity in modulating vascular tone and renal water reabsorption. It serves as a key active pharmaceutical ingredient (API) and reference standard for researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors.

Application

• Pharmaceutical API: Core active ingredient in formulations for the treatment of diabetes insipidus and certain bleeding disorders.
• Biochemical Research: Critical tool for studying vasopressin receptor (V1a, V2) signaling pathways, cellular physiology, and hormone action.
• Reference Standard: Used in quality control laboratories for the identification and assay of vasopressin in pharmaceutical products via HPLC, MS, or other analytical methods.
• Diagnostic Reagent: Component in diagnostic kits and assays for evaluating endocrine function and related disorders.
• Peptide Chemistry Studies: Serves as a model compound in peptide synthesis, stability testing, and structural analysis research.

Basic Information

Product Name	Argipressine
CAS No.	113-79-1
Molecular Formula	C₄₆H₆₅N₁₅O₁₂S₂
Molecular Weight	1084.2 g/mol
Synonyms	Vasopressin; 8-Arginine vasopressin; AVP; Antidiuretic hormone (ADH); Argipressin; β-Hypophamine; Pitressin; Pressyn; Diapid; Desmopressin precursor
EINECS	204-033-7

Quality Control

Our Argipressine is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identification by spectroscopic methods, purity assay by HPLC, and tests for related substances and residual solvents. We provide full traceability and support compliance with cGMP guidelines for API manufacturing. A detailed Certificate of Analysis (COA) is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. The product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage, consider desiccated conditions at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Bacterial Endotoxins	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.