Description

5-(4-Fluorophenyl)Pyridine-2-Carbonitrile is a high-purity fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both a fluorophenyl group and a nitrile functionality, makes it a versatile intermediate for constructing complex pharmacophores and functional materials. This compound is essential for R&D and production chemists in the pharmaceutical, agrochemical, and material science industries seeking to develop novel active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and central nervous system (CNS) drug discovery programs.
• Agrochemical Synthesis: Used in the research and manufacturing of advanced herbicides and fungicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or emissive materials for OLEDs.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes for bioimaging and diagnostic applications.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring fluorinated heterocyclic architectures.

Basic Information

Item	Details
Product Name	5-(4-Fluorophenyl)Pyridine-2-Carbonitrile
CAS No.	914349-75-0
Molecular Formula	C12H7FN2
Molecular Weight	198.20 g/mol
Synonyms	2-Cyano-5-(4-fluorophenyl)pyridine; 5-(4-Fluorophenyl)-2-pyridinecarbonitrile; 4-Fluoro-5-(2-cyanopyridin-5-yl)benzene; 5-(p-Fluorophenyl)picolinonitrile; 2-Pyridinecarbonitrile, 5-(4-fluorophenyl)-; 914349-75-0; 5-(4-Fluorophenyl)-2-cyanopyridine
EINECS	Contact for details

Quality Control

Every batch of 5-(4-Fluorophenyl)Pyridine-2-Carbonitrile is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency meet the stringent requirements of our global clientele. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance and regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Maximum Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.