Description

4-Hydroxy-3-Methoxy-Benzenesulfonyl Chloride is a versatile and highly reactive sulfonyl chloride derivative, serving as a critical building block in advanced organic synthesis. Its core value lies in its ability to introduce the sulfonyl functional group, enabling the creation of sulfonamides and sulfonate esters with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for creating sulfonamide-based therapeutics with potential antibacterial, diuretic, or enzyme-inhibiting activity.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and plant growth regulators where the sulfonyl moiety is integral to biological activity.
• Dye and Pigment Manufacturing: Acts as a reactive intermediate for introducing sulfonyl groups into dye molecules, enhancing solubility, color fastness, and fiber affinity.
• Polymer Modification: Employed to functionalize polymers and resins, imparting specific properties like improved hydrophilicity, adhesion, or chemical resistance.
• Chemical Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic pathways and creating specialized chemical libraries.
• Ligand and Catalyst Design: Serves as a starting material for synthesizing complex ligands and organocatalysts used in asymmetric synthesis and metal complexation.

Basic Information

Product Name	4-Hydroxy-3-Methoxy-Benzenesulfonyl Chloride
CAS No.	914261-11-3
Molecular Formula	C7H7ClO4S
Molecular Weight	222.65 g/mol
Synonyms	Vanillin Sulfonyl Chloride; 3-Methoxy-4-hydroxybenzenesulfonyl chloride; 4-Hydroxy-3-methoxybenzene-1-sulfonyl chloride; 2-Methoxy-4-(chlorosulfonyl)phenol; Guaiacol-4-sulfonyl chloride; Vanillic sulfonyl chloride; (4-Hydroxy-3-methoxyphenyl)sulfonyl chloride
EINECS	Contact for details

Quality Control

Our 4-Hydroxy-3-Methoxy-Benzenesulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise specifications for research and industrial use. Certificates of Analysis (COA) detailing all quality parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.