Description

(6-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid CAS NO 913839-73-3 is a high-value trifluoromethylpyridine derivative, a key building block in advanced organic synthesis. Its core value lies in the unique combination of the pyridine heterocycle and the trifluoromethyl group, which imparts desirable properties like enhanced metabolic stability and lipophilicity to target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitors, antiviral agents, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group improves efficacy and environmental profile.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes for studying biological processes and target engagement.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis projects and scale-up production under cGMP or ISO standards.

Basic Information

Product Name	(6-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid
CAS No.	913839-73-3
Molecular Formula	C8H6F3NO2
Molecular Weight	205.14 g/mol
Synonyms	2-(6-(Trifluoromethyl)pyridin-3-yl)acetic acid; 3-Pyridineacetic acid, 6-(trifluoromethyl)-; (6-(Trifluoromethyl)-3-pyridinyl)acetic Acid; 6-Trifluoromethylnicotinic acid, acetic acid derivative; 2-(6-(Trifluoromethyl)-3-pyridyl)acetic acid; TFMPAA; 913839-73-3 (CAS); 6-Trifluoromethyl-3-pyridylacetic acid
EINECS	Contact for details

Quality Control

Our (6-Trifluoromethyl-Pyridin-3-Yl)-Acetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications. Our quality commitment supports development and production under ISO, cGMP, and REACH compliance frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.