Description

3-Carboxy-4-Methoxyphenylboronic Acid is a functionalized boronic acid derivative that serves as a versatile building block in modern synthetic chemistry. Its molecular structure, featuring both a carboxylic acid and a boronic acid group, makes it a valuable precursor for the synthesis of complex molecules, particularly in pharmaceutical research and materials science. This compound is essential for chemists and researchers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for cross-coupling reactions and other advanced synthetic transformations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for Suzuki-Miyaura cross-coupling reactions to create biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides that require specific aromatic boronic acid motifs.
• Material Science Research: Employed in the development of organic electronic materials, such as polymers for OLEDs and organic photovoltaics, where its functional groups allow for precise molecular engineering.
• Chemical Biology & Proteomics: Acts as a ligand or handle in the development of chemical probes and sensors, leveraging the boronic acid group's affinity for diols.
• Academic & Industrial R&D: Serves as a critical reagent in method development and discovery chemistry within university and corporate research laboratories.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds and libraries.

Basic Information

Product Name	3-Carboxy-4-Methoxyphenylboronic Acid
CAS No.	913836-12-1
Molecular Formula	C9H11BO5
Molecular Weight	209.99 g/mol
Synonyms	(3-Carboxy-4-methoxyphenyl)boronic acid; 4-Methoxy-3-carboxyphenylboronic acid; 3-Borono-4-methoxybenzoic acid; 2-Methoxy-5-boronobenzoic acid; Boronic acid, B-(3-carboxy-4-methoxyphenyl)-; 913836-12-1; 4-Methoxy-3-boronobenzoic acid
EINECS	Contact for details

Quality Control

Our 3-Carboxy-4-Methoxyphenylboronic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (argon or nitrogen) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.