Description

5-Carboxy-2-Chlorobenzeneboronic Acid is a high-purity boronic acid derivative that serves as a critical building block in modern synthetic chemistry. Its bifunctional nature, featuring both a boronic acid and a carboxylic acid group, makes it an exceptionally versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by researchers and process chemists in the pharmaceutical and agrochemical industries for applications in Suzuki-Miyaura cross-coupling and other catalytic transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring a chlorinated benzoic acid scaffold.
• Suzuki-Miyaura Cross-Coupling: The boronic acid functional group enables efficient palladium-catalyzed carbon-carbon bond formation with aryl or vinyl halides, a cornerstone reaction in medicinal chemistry.
• Ligand Synthesis: Used to create novel bidentate or tridentate ligands for catalysis, leveraging both the boronic acid and carboxylic acid moieties for metal coordination.
• Agrochemical Research: Employed in the development of new herbicides, fungicides, and plant growth regulators that incorporate halogenated aromatic structures.
• Material Science: Serves as a monomer or cross-linking agent for the development of advanced polymeric materials, such as self-healing gels or sensors.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes due to its ability to form stable esters and amides.

Basic Information

Product Name	5-Carboxy-2-Chlorobenzeneboronic Acid
CAS No.	913835-75-3
Molecular Formula	C7H6BClO4
Molecular Weight	200.38 g/mol
Synonyms	(5-Carboxy-2-chlorophenyl)boronic acid; 2-Chloro-5-carboxyphenylboronic acid; 2-Chlorobenzene-1,4-dicarboxylic acid (boronic acid derivative); Benzoic acid, 2-chloro-5-borono-; 5-Borono-2-chlorobenzoic acid
EINECS	Contact for details

Quality Control

Our 5-Carboxy-2-Chlorobenzeneboronic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and NMR for structural confirmation, to ensure it meets the 98% minimum purity specification. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive). For long-term storage, consider using desiccants or storing under an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.