Description

Trans Latanoprost is a synthetic prostaglandin F2α analog and a key stereoisomer of the active pharmaceutical ingredient Latanoprost. This compound is of significant interest in pharmaceutical research and development, particularly for its role in the synthesis and study of ocular therapeutics. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of novel treatments for glaucoma and ocular hypertension. The high-purity grade of this material ensures reliable and reproducible results in critical analytical and synthetic applications.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of prostaglandin-based active pharmaceutical ingredients (APIs).
• Ophthalmic Drug Research: Used in R&D for developing and optimizing new formulations targeting intraocular pressure reduction.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.
• Process Chemistry: Utilized in scale-up studies and route optimization for the commercial manufacturing of related prostaglandin analogs.
• Biochemical Studies: Applied in pharmacological research to investigate the structure-activity relationships (SAR) of prostaglandin receptors.

Basic Information

Product Name	Trans Latanoprost
CAS No.	913258-34-1
Molecular Formula	C₂₆H₄₀O₅
Molecular Weight	432.59 g/mol
Synonyms	(5Z,13E,15R,16R)-9,11,15-Trihydroxy-16-(3-trifluoromethylphenoxy)-17,18,19,20-tetranor-5,13-prostadienoic Acid Isopropyl Ester; 15(R)-Latanoprost; Latanoprost Impurity F (Trans-isomer); 15-epi-Latanoprost; Latanoprost Related Compound F; Xalatan Impurity F; Prostaglandin F2α analog (trans); UNII-6Z5B6HVF6O
EINECS	Contact for details

Quality Control

Our Trans Latanoprost is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the exact specifications and test results. We adhere to cGMP principles where applicable to support our clients' regulatory compliance.

Storage

Preserve in a tightly closed container, protected from light. Store unopened vials at -20°C or below. For long-term storage under an inert atmosphere (nitrogen or argon) is recommended to prevent oxidation. Once opened, the material should be used promptly and any remaining product should be handled under controlled conditions to minimize exposure to moisture and air.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.