Description

B-[4-[[(4-Methylphenyl)Amino]Carbonyl]Phenyl]Boronic Acid is a specialized organoboron compound featuring a biaryl amide structure, making it a valuable building block in modern synthetic chemistry. Its core value lies in its dual functionality, serving as both a boronic acid for Suzuki-Miyaura cross-coupling reactions and a protected amide group for further derivatization. This compound is essential for researchers and manufacturers in the pharmaceutical and advanced materials sectors who require high-purity intermediates for constructing complex molecular architectures, such as active pharmaceutical ingredients (APIs) and organic electronic materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting kinase inhibition or other protein-protein interactions.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boronic acid coupling partner for the formation of carbon-carbon bonds between aromatic rings, a fundamental reaction in medicinal chemistry.
• Ligand Synthesis for Catalysis: Used in the development of novel bidentate or tridentate ligands for transition metal catalysts.
• Material Science Research: Employed in the creation of organic semiconductors, liquid crystals, or metal-organic frameworks (MOFs) due to its rigid, planar structure.
• Chemical Biology Probes: Utilized as a building block for synthesizing molecules that interact with biological targets, aiding in drug discovery and diagnostic tool development.
• Agrochemical Synthesis: Acts as an intermediate in the development of new herbicides or fungicides with specific activity profiles.

Basic Information

Product Name	B-[4-[[(4-Methylphenyl)Amino]Carbonyl]Phenyl]Boronic Acid
CAS No.	913198-24-0
Molecular Formula	C14H14BNO3
Molecular Weight	255.08 g/mol
Synonyms	4'-(4-Methylbenzamido)phenylboronic acid; [4-(4-Methylbenzoylamino)phenyl]boronic acid; B-[4-[(4-Methylbenzoyl)amino]phenyl]boronic acid; 4-Carbamoylphenylboronic acid, N-(4-methylphenyl)-; 913198-24-0; p-(p-Toluamido)phenylboronic acid; 4-[(4-Methylphenyl)carbamoyl]benzeneboronic acid
EINECS	Contact for details

Quality Control

Our B-[4-[[(4-Methylphenyl)Amino]Carbonyl]Phenyl]Boronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is light-sensitive (store away from light). Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.