Description

6-(Difluoromethyl)Pyridin-3-Amine is a specialized fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the unique reactivity imparted by the difluoromethyl group adjacent to the amine functionality on the pyridine ring. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical sectors, where it is used to develop novel active ingredients with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides, fungicides, and insecticides, where the difluoromethyl group can improve metabolic stability and bioavailability.
• Material Science Precursor: Employed in the synthesis of functionalized ligands, metal-organic frameworks (MOFs), and advanced polymers for specialized applications.
• Chemical Research & Development: Serves as a versatile scaffold in academic and industrial R&D for exploring new chemical spaces and reaction pathways in fluoroorganic chemistry.

Basic Information

Product Name	6-(Difluoromethyl)Pyridin-3-Amine
CAS No.	913090-41-2
Molecular Formula	C6H6F2N2
Molecular Weight	144.12 g/mol
Synonyms	3-Amino-6-(difluoromethyl)pyridine; 6-(Difluoromethyl)-3-pyridinamine; 5-Amino-2-(difluoromethyl)pyridine; 2-(Difluoromethyl)-5-aminopyridine; 3-Pyridinamine, 6-(difluoromethyl)-; 913090-41-2; 6-Difluoromethyl-pyridin-3-ylamine
EINECS	Contact for details

Quality Control

Our 6-(Difluoromethyl)Pyridin-3-Amine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.