Description

6-Bromopyridine-2-Sulfonyl Chloride is a high-purity, reactive organosulfur intermediate essential for advanced chemical synthesis. Its value lies in the dual functionality of the bromo and sulfonyl chloride groups, enabling precise derivatization and the construction of complex molecular architectures. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the pyridine-sulfonamide scaffold is prevalent.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in transition metal catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of functional polymers and advanced organic materials with specific electronic or surface properties.
• Chemical Biology Probes: Utilized to create sulfonamide-based probes and linkers for studying protein-ligand interactions and enzyme activity.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical and custom synthesis houses serving the life sciences sector.

Basic Information

Product Name	6-Bromopyridine-2-Sulfonyl Chloride
CAS No.	912934-77-1
Molecular Formula	C5H3BrClNO2S
Molecular Weight	256.50 g/mol
Synonyms	2-Bromo-6-pyridinesulfonyl chloride; 6-Bromo-2-pyridinesulfonyl chloride; 2-Pyridinesulfonyl chloride, 6-bromo-; 6-Bromopyridine-2-sulphonyl chloride; 6-Bromo-2-pyridylsulfonyl chloride; 6-Bromopyridine-2-sulfonic acid chloride
EINECS	Contact for details

Quality Control

Our 6-Bromopyridine-2-Sulfonyl Chloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) documenting all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.