Description

Thiovardenafil CAS NO 912576-24-0 is a high-purity pharmaceutical intermediate and research chemical, structurally related to the PDE5 inhibitor class. It is a critical building block for advanced pharmaceutical research and development, particularly in the study of urological and cardiovascular therapeutics. This compound is essential for R&D laboratories, academic institutions, and pharmaceutical manufacturers engaged in the synthesis and investigation of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the research and development of PDE5 inhibitor analogs.
• Active Pharmaceutical Ingredient (API) Research: Used as a reference standard and starting material in the study of new therapeutic agents for erectile dysfunction and pulmonary arterial hypertension.
• Biochemical Research: Valuable tool compound for in-vitro and in-vivo studies targeting phosphodiesterase enzymes.
• Academic & Institutional R&D: Serves as a high-purity chemical for pharmacological and medicinal chemistry research programs.
• Process Development: Employed in the optimization and scale-up of synthetic routes for related pharmaceutical compounds.
• Analytical Standard: Used for method development, validation, and quality control testing in analytical laboratories.

Basic Information

Product Name	Thiovardenafil
CAS No.	912576-24-0
Molecular Formula	C23H32N6O4S2
Molecular Weight	520.67 g/mol
Synonyms	2-[2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-5-methyl-7-propyl-1H-imidazo[5,1-f][1,2,4]triazin-4(3H)-one; Thiovardenafil; Vardenafil thio analog; PDE5 inhibitor intermediate
EINECS	Contact for details

Quality Control

Our Thiovardenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis to ensure it meets stringent research-grade specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.