Description

Hydroxyhomosildenafil is a high-purity pharmaceutical intermediate and reference standard. This compound is critical for research and development in the pharmaceutical sector, particularly for analytical method validation and quality control processes. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories requiring precise and reliable chemical standards.

Application

• Pharmaceutical Reference Standard: Used for the calibration of analytical instruments and validation of testing methods (e.g., HPLC, LC-MS) in quality control laboratories.
• Active Pharmaceutical Ingredient (API) Intermediate: Serves as a key synthetic precursor in the research and development of specialized pharmaceutical compounds.
• Metabolite Studies: Employed in pharmacological and toxicological research to study drug metabolism and pharmacokinetics.
• Impurity Profiling: Acts as a certified impurity standard to identify and quantify related substances in final drug products, ensuring compliance with regulatory purity specifications.
• Forensic Analysis: Used as a qualitative standard in forensic laboratories for the identification of substances in compliance and safety testing.

Basic Information

Product Name	Hydroxyhomosildenafil
CAS No.	139755-85-4
Molecular Formula	C23H32N6O5S
Molecular Weight	504.60 g/mol
Synonyms	Hydroxyhomosildenafil; 5-[2-Ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl]-1-methyl-3-propyl-1,6-dihydro-7H-pyrazolo[4,3-d]pyrimidin-7-one; Homosildenafil hydroxyl analog; Sildenafil hydroxyl analog; Thiosildenafil analog; Research Compound 139755-85-4
EINECS	Contact for details

Quality Control

Our Hydroxyhomosildenafil is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for identification, and residual solvent analysis to ensure it meets stringent specifications for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.